021-51111890
购物车（0）
sales@molnova.cn
Carbenoxolone disodium
CAS No. 7421-40-1
Carbenoxolone disodium ( Biogastrone | Bioral | Carbenoxolone sodium | Duogastrone | Pyrogastrone | Sanodin )
产品货号. M15836 CAS No. 7421-40-1
一种从甘草根中提取的制剂。它用于治疗消化道溃疡，特别是胃溃疡。抗利尿副作用很常见，但该药物的毒性较低。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 25MG | ￥535 | 有现货 |
|
| 50MG | ￥786 | 有现货 |
|
| 100MG | ￥1345 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Carbenoxolone disodium
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述一种从甘草根中提取的制剂。它用于治疗消化道溃疡，特别是胃溃疡。抗利尿副作用很常见，但该药物的毒性较低。
-
产品描述An agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity.
-
体外实验Cell Viability Assay Cell Line:HaCaT cells Concentration:6 μM, 12 μM, 30 μM, 60 μM, 150 μM Incubation Time:Pre-treatment 1 hour Result:Had no toxicity until 48 hours at high dose in virus-infected cells. Western Blot Analysis Cell Line:HaCaT cells Concentration:30 μM Incubation Time:Pre-treatment 1 hour Result:Presented an obvious upregulation of A27.
-
体内实验——
-
同义词Biogastrone | Bioral | Carbenoxolone sodium | Duogastrone | Pyrogastrone | Sanodin
-
通路Cytoskeleton/Cell Adhesion Molecules
-
靶点Gap Junction Protein
-
受体Gap Junction Protein
-
研究领域Inflammation/Immunology
-
适应症Psoriasis
化学信息
-
CAS Number7421-40-1
-
分子量614.72
-
分子式C34H48Na2O7
-
纯度>98% (HPLC)
-
溶解度Water: 100 mM
-
SMILESCC(C)([C@](CC[C@@]([C@@]1(CC[C@]2(CC[C@](C([O-])=O)(C[C@]2(C1=C3)[H])C)C)C)4C)5[H])[C@@H](OC(CCC([O-])=O)=O)CC[C@]5(C)[C@@]4([H])C3=O.[Na+].[Na+]
-
化学全称sodium (2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-((3-carboxylatopropanoyl)oxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylate
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Hausmann W, Tárnoky AL. Br J Pharmacol ChemOthers. 1966 Feb;26(2):412-20.
产品手册
关联产品
-
Gap19
Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.
-
GAP-134
Danegaptide (GAP-134) 是一种有效的，选择性的，具有口服活性的 gap-junction 修饰剂，具有抗心律不齐的作用。
-
TAT-Gap19
Cx43 hemichannel blocker (IC50 ~7 μM). No significant affinity for gap junctions or Panx1 channels. N-terminal transactivator of transcription (TAT) motif promotes membrane permeability and increases inhibitory effect of Gap19. Active in vivo. Brain penetrant.
